Shenzhen Gnotobio Biotechnology Co., Ltd. was established in October 2019 as a high-tech enterprise specializing in germ-free animal models and animal experiment services. The company was founded by experts in the fields of microbiome and germ-free animal research, with its core team bringing together scientists from internationally renowned institutions such as the Broad Institute, Harvard University, Massachusetts Institute of Technology (MIT), Columbia University, and Johns Hopkins University.
The company has obtained both the "Germ-free Animal Production License" and the "Germ-free Animal Use License". It has established two major experimental bases — one in Songshan Lake, Dongguan, and another in Chaohu, Hefei — with a total floor area exceeding 5,000 square meters. These bases form a dual-hub service network covering the Pearl River Delta and Yangtze River Delta regions, enabling the company to meet scientific research needs across China. Its main business includes:
● Germ-free and SPF-grade mice: Covering strains such as C57BL/6J, BALB/C, and nude mice, providing full-process support including contract breeding, contract housing, rapid expansion, and IVF rederivation.
● Professional CRO technical services: Including outsourced germ-free animal-related experiments such as standardized microbiota transplantation, disease model construction, and efficacy evaluation.
● Genetically engineered mouse customization services: Professionally providing gene knockout, gene knock-in, transgenic mouse, and gene-edited rat models.
● P2 laboratory services: Relying on a compliant P2 (BSL-2) platform, we provide safe and reliable research support at the cellular, molecular, and animal levels for projects involving hazardous pathogens, recombinant microorganisms, and related studies.
Driven by the dual-core model of "equipment R&D + experimental services," the company is committed to providing high-quality, standardized one-stop solutions for germ-free animal research to biopharmaceutical companies and research institutions.

As the core experimental support pillar of Xbiome's AI-driven microbiome research and industrialization translation platform, Gnotobio Biotechnology has always been committed to building a complete closed loop from data to validation. Starting as the first certified germ-free animal platform in South China, we have grown into a comprehensive experimental animal service system covering germ-free mice, gene-edited models, and humanized models, supporting critical validation for innovative drugs from target discovery to preclinical research.

In frontier fields such as microbiome research and immunotherapy, reliable animal models serve as a key bridge connecting computational predictions with biological mechanisms. With our standardized sterility assurance system and professional model customization capabilities, we provide our partners with traceable and reproducible experimental foundations, helping transform cutting-edge data into biologically meaningful discoveries with translational value.

We look forward to leveraging our robust platform capabilities to stand shoulder to shoulder with more Chinese innovators, advancing the scientific journey from algorithms to therapies in the intricate details of life sciences.